ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1)

2021-06-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
Vms1,ZNF744

Other Information

Locus ID:

NCBI: 55139
MIM: 617541
HGNC: 25527
Ensembl: ENSG00000163516

Variants:

dbSNP: 55139
ClinVar: 55139
TCGA: ENSG00000163516
COSMIC: ANKZF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163516ENST00000323348Q9H8Y5
ENSG00000163516ENST00000323348A0A024R464
ENSG00000163516ENST00000409849B8ZZS4
ENSG00000163516ENST00000410034Q9H8Y5
ENSG00000163516ENST00000410034A0A024R464
ENSG00000163516ENST00000416565C9J5H7
ENSG00000163516ENST00000435521F8WD44
ENSG00000163516ENST00000436226C9JQZ3
ENSG00000163516ENST00000447157C9K022
ENSG00000163516ENST00000453432C9JS61

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386665412024Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.0
386665412024Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.0
312579222019High ANKZF1 expression is associated with poor overall survival and recurrence-free survival in colon cancer.11
312579222019High ANKZF1 expression is associated with poor overall survival and recurrence-free survival in colon cancer.11
296323122018Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.66
302448312018Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.48
296323122018Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.66
302448312018Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.48
283027252017Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease.14
283027252017Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease.14

Citation

Dessen P

ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58191/js/lib/img/logo-atlas-4.svg