DIP2A (disco interacting protein 2 homolog A)

2021-06-01  

Identity

HGNC
DIP2A
LOCATION
21q22.3
LOCUSID
23181
ALIAS
C21orf106,DIP2

Other Information

Locus ID:

NCBI: 23181
MIM: 607711
HGNC: 17217
Ensembl: ENSG00000160305

Variants:

dbSNP: 23181
ClinVar: 23181
TCGA: ENSG00000160305
COSMIC: DIP2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160305ENST00000400274Q14689
ENSG00000160305ENST00000417564Q14689
ENSG00000160305ENST00000435722Q14689
ENSG00000160305ENST00000457905Q14689
ENSG00000160305ENST00000466639Q14689
ENSG00000160305ENST00000651436A0A494C143

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378979752023Disco interacting protein 2 homolog A (DIP2A): A key component in the regulation of brain disorders.0
378979752023Disco interacting protein 2 homolog A (DIP2A): A key component in the regulation of brain disorders.0
305421202019Fstl1/DIP2A/MGMT signaling pathway plays important roles in temozolomide resistance in glioblastoma.19
305421202019Fstl1/DIP2A/MGMT signaling pathway plays important roles in temozolomide resistance in glioblastoma.19
301106362018Blocking the FSTL1-DIP2A Axis Improves Anti-tumor Immunity.17
301106362018Blocking the FSTL1-DIP2A Axis Improves Anti-tumor Immunity.17
264523392016Genetic variant in DIP2A gene is associated with developmental dyslexia in Chinese population.16
264523392016Genetic variant in DIP2A gene is associated with developmental dyslexia in Chinese population.16
200540022010DIP2A functions as a FSTL1 receptor.57
208606222010DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins.34
200540022010DIP2A functions as a FSTL1 receptor.57
208606222010DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins.34

Citation

Dessen P

DIP2A (disco interacting protein 2 homolog A)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58277/case-report-explorer/haematological-explorer/css/template-nav.css