SH2D5 (SH2 domain containing 5)

2021-06-01  

Identity

HGNC
SH2D5
LOCATION
1p36.12
LOCUSID
400745
ALIAS
-

Other Information

Locus ID:

NCBI: 400745
HGNC: 28819
Ensembl: ENSG00000189410

Variants:

dbSNP: 400745
ClinVar: 400745
TCGA: ENSG00000189410
COSMIC: SH2D5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189410ENST00000375031Q6ZV89
ENSG00000189410ENST00000444387Q6ZV89
ENSG00000189410ENST00000447746J3KQT6
ENSG00000189410ENST00000517430E5RGV2
ENSG00000189410ENST00000518294E5RJW5
ENSG00000189410ENST00000519434E5RGJ3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA445218Pancreatic NeoplasmsDiseaseClinicalAnnotationassociatedPD22838950
PA449748gemcitabineChemicalClinicalAnnotationassociatedPD22838950

References

Pubmed IDYearTitleCitations
371875272023Prognostic significance of SH2D5 expression in lung adenocarcinoma and its relation to immune cell infiltration.0
371875272023Prognostic significance of SH2D5 expression in lung adenocarcinoma and its relation to immune cell infiltration.0
306590972019Hepatitis B virus X protein-induced SH2 domain-containing 5 (SH2D5) expression promotes hepatoma cell growth via an SH2D5-transketolase interaction.15
306590972019Hepatitis B virus X protein-induced SH2 domain-containing 5 (SH2D5) expression promotes hepatoma cell growth via an SH2D5-transketolase interaction.15
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

SH2D5 (SH2 domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58336/js/lib/js/lib/jquery-3.5.1.min.js