AHSA1 (activator of HSP90 ATPase activity 1)

2003-05-01  

Identity

HGNC
AHSA1
LOCATION
14q24.3
LOCUSID
10598
ALIAS
AHA1,C14orf3,hAha1,p38
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10598
MIM: 608466
HGNC: 1189
Ensembl: ENSG00000100591

Variants:

dbSNP: 10598
ClinVar: 10598
TCGA: ENSG00000100591
COSMIC: AHSA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100591ENST00000216479O95433
ENSG00000100591ENST00000535854O95433
ENSG00000100591ENST00000553374H0YJG7
ENSG00000100591ENST00000555133G3V438
ENSG00000100591ENST00000555517G3V3W9
ENSG00000100591ENST00000555729H0YJU2
ENSG00000100591ENST00000556369H0YJ63

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365203072023p23 and Aha1: Distinct Functions Promote Client Maturation.1
374867052023Human Aha1's N-terminal extension confers it holdase activity in vitro.2
365203072023p23 and Aha1: Distinct Functions Promote Client Maturation.1
374867052023Human Aha1's N-terminal extension confers it holdase activity in vitro.2
350345962022Identification of AHSA1 as a Potential Therapeutic Target for Breast Cancer: Bioinformatics Analysis and in vitro Studies.1
357577282022The Prognostic and Immunotherapeutic Significance of AHSA1 in Pan-Cancer, and Its Relationship With the Proliferation and Metastasis of Hepatocellular Carcinoma.9
350345962022Identification of AHSA1 as a Potential Therapeutic Target for Breast Cancer: Bioinformatics Analysis and in vitro Studies.1
357577282022The Prognostic and Immunotherapeutic Significance of AHSA1 in Pan-Cancer, and Its Relationship With the Proliferation and Metastasis of Hepatocellular Carcinoma.9
334689902021AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma.19
334689902021AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma.19
317829422020Aha-type co-chaperones: the alpha or the omega of the Hsp90 ATPase cycle?5
317829422020Aha-type co-chaperones: the alpha or the omega of the Hsp90 ATPase cycle?5
312991342019Dynamic Aha1 co-chaperone binding to human Hsp90.16
312991342019Dynamic Aha1 co-chaperone binding to human Hsp90.16
288273212017Hsp90 activator Aha1 drives production of pathological tau aggregates.55

Citation

Dessen P

AHSA1 (activator of HSP90 ATPase activity 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/599/gene-fusions-explorer/css/css/template-card.css