ACER1 (alkaline ceramidase 1)

2014-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
ALKCDase1,ASAH3
FUSION GENES

Other Information

Locus ID:

NCBI: 125981
MIM: 613491
HGNC: 18356
Ensembl: ENSG00000167769

Variants:

dbSNP: 125981
ClinVar: 125981
TCGA: ENSG00000167769
COSMIC: ACER1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167769ENST00000301452Q8TDN7

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Sphingolipid metabolismKEGGko00600
Sphingolipid metabolismKEGGhsa00600
Metabolic pathwaysKEGGhsa01100
Sphingosine biosynthesisKEGGM00099
Sphingosine biosynthesisKEGGhsa_M00099
Sphingolipid signaling pathwayKEGGhsa04071
Sphingolipid signaling pathwayKEGGko04071
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Sphingolipid metabolismREACTOMER-HSA-428157
Sphingolipid de novo biosynthesisREACTOMER-HSA-1660661

References

Pubmed IDYearTitleCitations
177135732008Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes.39
119153422002[Molecular evolution of neutral ceramidase: signalling molecule and virulence factor].1

Citation

Dessen P

ACER1 (alkaline ceramidase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60082/acer1-(alkaline-ceramidase-1)