ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A)

2014-11-01  

Identity

HGNC
ANKS1A
LOCATION
6p21.31
LOCUSID
23294
ALIAS
ANKS1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23294
MIM: 608994
HGNC: 20961
Ensembl: ENSG00000064999

Variants:

dbSNP: 23294
ClinVar: 23294
TCGA: ENSG00000064999
COSMIC: ANKS1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000064999ENST00000360359Q92625
ENSG00000064999ENST00000649117A0A3B3ISP1
ENSG00000064999ENST00000650178A0A3B3ITU5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381235472023ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.1
381235472023ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.1
367174542022The Role of the Adapter Protein Anks1a in the Regulation of Breast Cancer Cell Motility.1
367174542022The Role of the Adapter Protein Anks1a in the Regulation of Breast Cancer Cell Motility.1
341309402021ANKS1A genotype predicts cardiovascular events in patients with familial hypercholesterolemia.2
341309402021ANKS1A genotype predicts cardiovascular events in patients with familial hypercholesterolemia.2
276196422016Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.17
276196422016Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.17
261200792015Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.3
261200792015Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.3
232395782013Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights.6
238255232013Odin (ANKS1A) modulates EGF receptor recycling and stability.12
232395782013Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights.6
238255232013Odin (ANKS1A) modulates EGF receptor recycling and stability.12
222919912012RINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odin.7

Citation

Dessen P

ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60369/js/css/lib/bootstrap.min.css