APOBEC4 (apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4)

2014-11-01  

Identity

HGNC
APOBEC4
LOCATION
1q25.3
LOCUSID
403314
ALIAS
C1orf169

Other Information

Locus ID:

NCBI: 403314
MIM: 609908
HGNC: 32152
Ensembl: ENSG00000173627

Variants:

dbSNP: 403314
ClinVar: 403314
TCGA: ENSG00000173627
COSMIC: APOBEC4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173627ENST00000308641Q8WW27

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
mRNA EditingREACTOMER-HSA-75072
mRNA Editing: C to U ConversionREACTOMER-HSA-72200
Formation of the EditosomeREACTOMER-HSA-75094

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
272496462016APOBEC4 Enhances the Replication of HIV-1.15
272496462016APOBEC4 Enhances the Replication of HIV-1.15
199111242009APOBEC deaminases-mutases with defensive roles for immunity.16
199111242009APOBEC deaminases-mutases with defensive roles for immunity.16
160822232005APOBEC4, a new member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases predicted by computational analysis.64
160822232005APOBEC4, a new member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases predicted by computational analysis.64

Citation

Dessen P

APOBEC4 (apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60429/meetings/favicon/favicon/favicon-32x32.png