AREL1 (apoptosis resistant E3 ubiquitin protein ligase 1)

2014-11-01  

Identity

HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
FIEL1,KIAA0317
FUSION GENES

Other Information

Locus ID:

NCBI: 9870
MIM: 615380
HGNC: 20363
Ensembl: ENSG00000119682

Variants:

dbSNP: 9870
ClinVar: 9870
TCGA: ENSG00000119682
COSMIC: AREL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119682ENST00000356357O15033
ENSG00000119682ENST00000481010H0YJ69
ENSG00000119682ENST00000490805H0YJK5
ENSG00000119682ENST00000553279G3V5P7
ENSG00000119682ENST00000553411H0YJF1
ENSG00000119682ENST00000554070H0YJ67
ENSG00000119682ENST00000555249G3V245
ENSG00000119682ENST00000555330G3V2B5
ENSG00000119682ENST00000556202G3V506

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
271621392016Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4.15
317325612019Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities in vitro.0

Citation

Dessen P

AREL1 (apoptosis resistant E3 ubiquitin protein ligase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60454/arel1