CLNS1A (chloride nucleotide-sensitive channel 1A)

CLNS1A (chloride nucleotide-sensitive channel 1A)

2014-11-01 Affiliation

Identity

HGNC

LOCATION

11q14.1

LOCUSID

ALIAS

CLCI,CLNS1B,ICln

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1207
MIM: 602158
HGNC: 2080
Ensembl: ENSG00000074201

Variants:

dbSNP: 1207
ClinVar: 1207
TCGA: ENSG00000074201
COSMIC: CLNS1A

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000074201	ENST00000263309	J3KN38
ENSG00000074201	ENST00000525064	E9PJF4
ENSG00000074201	ENST00000525428	P54105
ENSG00000074201	ENST00000526009	H0YEN9
ENSG00000074201	ENST00000526761	U3KPU0
ENSG00000074201	ENST00000527133	E9PQ83
ENSG00000074201	ENST00000528364	P54105
ENSG00000074201	ENST00000532069	E9PMI6

Expression (GTEx)

0

10

20

30

40

50

60

70

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
RNA transport	KEGG	ko03013
RNA transport	KEGG	hsa03013
Gene Expression	REACTOME	R-HSA-74160
Metabolism of non-coding RNA	REACTOME	R-HSA-194441
snRNP Assembly	REACTOME	R-HSA-191859

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
37070251	2023	O-GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β-catenin signalling.	3
37070251	2023	O-GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β-catenin signalling.	3
32999000	2020	Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer.	18
32999000	2020	Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer.	18
24298023	2014	Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene.	8
24298023	2014	Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene.	8
21081503	2011	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	79
21917931	2011	The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume.	8
21081503	2011	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	79
21917931	2011	The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume.	8
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
15905169	2005	ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4.	18
16087681	2005	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.	17
15905169	2005	ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4.	18

Citation

Dessen P

CLNS1A (chloride nucleotide-sensitive channel 1A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61898/gene-explorer/js/lib/bootstrap.min.js