CRYGB (crystallin gamma B)

2014-11-01 Affiliation

Identity

HGNC

CRYGB

LOCATION

2q33.3

LOCUSID

1419

ALIAS

CRYG2,CTRCT39

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1419
MIM: 123670
HGNC: 2409
Ensembl: ENSG00000182187

Variants:

dbSNP: 1419
ClinVar: 1419
TCGA: ENSG00000182187
COSMIC: CRYGB

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000182187	ENST00000260988	P07316

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
28013006	2017	Glycation of human γB-crystallin: A biophysical investigation.	3
28013006	2017	Glycation of human γB-crystallin: A biophysical investigation.	3
26552302	2015	[ALLELIC VARIANT FREQUENCY OF PROMOTER (G(-47)-->A) γ-CRYSTALLIN GENE AFFECTS THE LEVEL OF ITS EXPRESSION IN PLATELETS].	0
26552302	2015	[ALLELIC VARIANT FREQUENCY OF PROMOTER (G(-47)-->A) γ-CRYSTALLIN GENE AFFECTS THE LEVEL OF ITS EXPRESSION IN PLATELETS].	0
23288985	2012	Novel crystallin gamma B mutations in a Kuwaiti family with autosomal dominant congenital cataracts reveal genetic and clinical heterogeneity.	10
23288985	2012	Novel crystallin gamma B mutations in a Kuwaiti family with autosomal dominant congenital cataracts reveal genetic and clinical heterogeneity.	10
21941057	2011	Polymorphisms of the gamma crystallin A and B genes among Indian patients with pediatric cataract.	3
21941057	2011	Polymorphisms of the gamma crystallin A and B genes among Indian patients with pediatric cataract.	3
20621668	2010	Partially folded aggregation intermediates of human gammaD-, gammaC-, and gammaS-crystallin are recognized and bound by human alphaB-crystallin chaperone.	34
20800603	2010	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	14
20621668	2010	Partially folded aggregation intermediates of human gammaD-, gammaC-, and gammaS-crystallin are recognized and bound by human alphaB-crystallin chaperone.	34
20800603	2010	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	14
19384013	2009	Analysis of single nucleotide polymorphisms of CRYGA and CRYGB genes in control population of western Indian origin.	2
19384013	2009	Analysis of single nucleotide polymorphisms of CRYGA and CRYGB genes in control population of western Indian origin.	2
19384013	2009	Analysis of single nucleotide polymorphisms of CRYGA and CRYGB genes in control population of western Indian origin.	2

Citation

Dessen P

CRYGB (crystallin gamma B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62110/case-report-explorer/css/card-gene.css