ERI1 (exoribonuclease 1)

2014-11-01  

Identity

HGNC
LOCATION
8p23.1
LOCUSID
ALIAS
3HEXO,HEXO,THEX1
FUSION GENES

Other Information

Locus ID:

NCBI: 90459
MIM: 608739
HGNC: 23994
Ensembl: ENSG00000104626

Variants:

dbSNP: 90459
ClinVar: 90459
TCGA: ENSG00000104626
COSMIC: ERI1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104626ENST00000250263Q8IV48
ENSG00000104626ENST00000250263A0A024R355
ENSG00000104626ENST00000519292Q8IV48
ENSG00000104626ENST00000519292A0A024R355
ENSG00000104626ENST00000520684E5RIV7
ENSG00000104626ENST00000521844E5RJM3

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373528602023Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans.0
373528602023Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans.0
329602652020Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.4
329602652020Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.4
233290462013Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex.67
233290462013Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex.67
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
169120462006Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA.35
169120462006Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA.35
149611222004A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.256
154516622004Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP.22
149611222004A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.256
154516622004Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP.22
145360702003A 3' exonuclease that specifically interacts with the 3' end of histone mRNA.69

Citation

Dessen P

ERI1 (exoribonuclease 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62880/favicon/js/lib/bootstrap.min.js