FAM3D (FAM3 metabolism regulating signaling molecule D)

2014-11-01  

Identity

HGNC
FAM3D
LOCATION
3p14.2
LOCUSID
131177
ALIAS
EF7,OIT1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 131177
MIM: 608619
HGNC: 18665
Ensembl: ENSG00000198643

Variants:

dbSNP: 131177
ClinVar: 131177
TCGA: ENSG00000198643
COSMIC: FAM3D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198643ENST00000358781Q96BQ1
ENSG00000198643ENST00000358781A0A0A8K9B4
ENSG00000198643ENST00000482623F8WCI4
ENSG00000198643ENST00000483787C9J5Z5
ENSG00000198643ENST00000489857C9JB68
ENSG00000198643ENST00000498347C9IZW7

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373011982023Targeting cytokine-like protein FAM3D lowers blood pressure in hypertension.2
374548712023Hepatocyte-secreted FAM3D ameliorates hepatic steatosis by activating FPR1-hnRNP U-GR-SCAD pathway to enhance lipid oxidation.0
373011982023Targeting cytokine-like protein FAM3D lowers blood pressure in hypertension.2
374548712023Hepatocyte-secreted FAM3D ameliorates hepatic steatosis by activating FPR1-hnRNP U-GR-SCAD pathway to enhance lipid oxidation.0
269661882016Identification of FAM3D as a new endogenous chemotaxis agonist for the formyl peptide receptors.20
269661882016Identification of FAM3D as a new endogenous chemotaxis agonist for the formyl peptide receptors.20
222263342012Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation.9
222263342012Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation.9
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
121607272002Cloning, expression, and initial characterization of a novel cytokine-like gene family.68
121607272002Cloning, expression, and initial characterization of a novel cytokine-like gene family.68

Citation

Dessen P

FAM3D (FAM3 metabolism regulating signaling molecule D)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63193/favicon/haematological-explorer/case-report-explorer/js/lib/popper.js