G2E3 (G2/M-phase specific E3 ubiquitin protein ligase)

2014-11-01  

Identity

HGNC
G2E3
LOCATION
14q12
LOCUSID
55632
ALIAS
KIAA1333,PHF7B
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55632
MIM: 611299
HGNC: 20338
Ensembl: ENSG00000092140

Variants:

dbSNP: 55632
ClinVar: 55632
TCGA: ENSG00000092140
COSMIC: G2E3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092140ENST00000206595Q7L622
ENSG00000092140ENST00000438909F5GX24
ENSG00000092140ENST00000547532F8W0F5
ENSG00000092140ENST00000548934H0YH90
ENSG00000092140ENST00000550944F8VY49
ENSG00000092140ENST00000552515H0YI49
ENSG00000092140ENST00000553504G3V483
ENSG00000092140ENST00000554714G3V3B6
ENSG00000092140ENST00000555429G3V5B6
ENSG00000092140ENST00000648008A0A3B3ISH7

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365178182022Comprehensive analysis of the expression, prognostic significance, and regulation pathway of G2E3 in breast cancer.1
365178182022Comprehensive analysis of the expression, prognostic significance, and regulation pathway of G2E3 in breast cancer.1
255931942015Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells.7
255931942015Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells.7
172393722007G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization.13
172393722007G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization.13

Citation

Dessen P

G2E3 (G2/M-phase specific E3 ubiquitin protein ligase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63638/img/case-report-explorer/js/lib/bootstrap.min.js