GBP6 (guanylate binding protein family member 6)

2014-11-01  

Identity

HGNC
LOCATION
1p22.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 163351
MIM: 612467
HGNC: 25395
Ensembl: ENSG00000183347

Variants:

dbSNP: 163351
ClinVar: 163351
TCGA: ENSG00000183347
COSMIC: GBP6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183347ENST00000370456Q6ZN66

Expression (GTEx)

0
100
200
300
400
500
600

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164713366Tumor necrosis factor alpha (TNF-alpha) inhibitorsChemicalClinicalAnnotationassociatedPD
PA443434Arthritis, RheumatoidDiseaseClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
204234812010Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.13

Citation

Dessen P

GBP6 (guanylate binding protein family member 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63728/gbp6