KIF16B (kinesin family member 16B)

2014-11-01  

Identity

HGNC
KIF16B
LOCATION
20p12.1
LOCUSID
55614
ALIAS
C20orf23,KISC20ORF,SNX23
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55614
MIM: 618171
HGNC: 15869
Ensembl: ENSG00000089177

Variants:

dbSNP: 55614
ClinVar: 55614
TCGA: ENSG00000089177
COSMIC: KIF16B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089177ENST00000354981Q96L93
ENSG00000089177ENST00000354981A0A140VK74
ENSG00000089177ENST00000355755A0A0A0MRC9
ENSG00000089177ENST00000408042Q96L93
ENSG00000089177ENST00000450176H0Y534
ENSG00000089177ENST00000635823A0A1B0GVS8
ENSG00000089177ENST00000636835A0A1B0GTU3

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231
KinesinsREACTOMER-HSA-983189
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
158826252005Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B.118
237492122013The kinesin KIF16B mediates apical transcytosis of transferrin receptor in AP-1B-deficient epithelia.26
223579492012The fusion of early endosomes induces molecular-motor-driven tubule formation and fission.16
224496492012Genome-wide association study of intelligence: additive effects of novel brain expressed genes.8
297369602018KIF16B is a candidate gene for a novel autosomal-recessive intellectual disability syndrome.0

Citation

Dessen P

KIF16B (kinesin family member 16B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64913/kif16b