LDB2 (LIM domain binding 2)

2014-11-01  

Identity

HGNC
LDB2
LOCATION
4p15.32
LOCUSID
9079
ALIAS
CLIM1,LDB-2,LDB1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9079
MIM: 603450
HGNC: 6533
Ensembl: ENSG00000169744

Variants:

dbSNP: 9079
ClinVar: 9079
TCGA: ENSG00000169744
COSMIC: LDB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169744ENST00000304523O43679
ENSG00000169744ENST00000441778O43679
ENSG00000169744ENST00000502640E9PFI4
ENSG00000169744ENST00000506732D6RAT1
ENSG00000169744ENST00000507464H0YA09
ENSG00000169744ENST00000508918E7EX95
ENSG00000169744ENST00000512345E9PGU0
ENSG00000169744ENST00000515064G5E9Y7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
364733692023LIM-domain binding protein 2 was down-regulated by miRNA-96-5p inhibited the proliferation, invasion and metastasis of lung cancer H1299 cells.1
364733692023LIM-domain binding protein 2 was down-regulated by miRNA-96-5p inhibited the proliferation, invasion and metastasis of lung cancer H1299 cells.1
336562682021Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia.2
338498222021[LIM-domain binding protein 2 regulated by m(6)A modification inhibits lung adenocarcinoma cell proliferation in vitro].3
336562682021Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia.2
338498222021[LIM-domain binding protein 2 regulated by m(6)A modification inhibits lung adenocarcinoma cell proliferation in vitro].3
289469382018LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells.6
289469382018LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells.6
249259742014Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis.14
249259742014Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis.14
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
199976232009Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study.62
199976232009Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study.62

Citation

Dessen P

LDB2 (LIM domain binding 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65217/js/lib/cancer-prone-explorer/js/web-card-_common.js