LRFN5 (leucine rich repeat and fibronectin type III domain containing 5)

LRFN5 (leucine rich repeat and fibronectin type III domain containing 5)

2014-11-01 Affiliation

Identity

HGNC

LOCATION

14q21.1

LOCUSID

ALIAS

C14orf146,FIGLER8,SALM5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 145581
MIM: 612811
HGNC: 20360
Ensembl: ENSG00000165379

Variants:

dbSNP: 145581
ClinVar: 145581
TCGA: ENSG00000165379
COSMIC: LRFN5

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000165379	ENST00000298119	Q96NI6
ENSG00000165379	ENST00000554120	G3V4N1
ENSG00000165379	ENST00000554171	G3V364

Expression (GTEx)

0

5

10

15

20

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
37280213	2023	LRFN5 and OLFM4 as novel potential biomarkers for major depressive disorder: a pilot study.	3
37280213	2023	LRFN5 and OLFM4 as novel potential biomarkers for major depressive disorder: a pilot study.	3
35088940	2022	LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions.	5
36266731	2022	CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis.	35
35088940	2022	LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions.	5
36266731	2022	CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis.	35
31152157	2019	Microdeletion of pseudogene chr14.232.a affects LRFN5 expression in cells of a patient with autism spectrum disorder.	9
31748543	2019	Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5.	11
31152157	2019	Microdeletion of pseudogene chr14.232.a affects LRFN5 expression in cells of a patient with autism spectrum disorder.	9
31748543	2019	Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5.	11
29348429	2018	Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation.	22
29348579	2018	Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation.	28
29348429	2018	Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation.	22
29348579	2018	Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation.	28
21736948	2011	The SALM/Lrfn family of leucine-rich repeat-containing cell adhesion molecules.	35

Citation

Dessen P

LRFN5 (leucine rich repeat and fibronectin type III domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68580/js/lib/popper.js