LSM12 (LSM12 homolog)

2014-11-01  

Identity

HGNC
LSM12
LOCATION
17q21.31
LOCUSID
124801
ALIAS
PNAS-135
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 124801
MIM: 611793
HGNC: 26407
Ensembl: ENSG00000161654

Variants:

dbSNP: 124801
ClinVar: 124801
TCGA: ENSG00000161654
COSMIC: LSM12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161654ENST00000293406Q3MHD2
ENSG00000161654ENST00000585388K7ELG9
ENSG00000161654ENST00000591247Q3MHD2

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376072182023Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12.2
376072182023Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12.2
354490732022Identification of RNA-splicing factor Lsm12 as a novel tumor-associated gene and a potent biomarker in Oral Squamous Cell Carcinoma (OSCC).8
373034932022LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathway.0
354490732022Identification of RNA-splicing factor Lsm12 as a novel tumor-associated gene and a potent biomarker in Oral Squamous Cell Carcinoma (OSCC).8
373034932022LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathway.0
343628922021Lsm12 is an NAADP receptor and a two-pore channel regulatory protein required for calcium mobilization from acidic organelles.30
343628922021Lsm12 is an NAADP receptor and a two-pore channel regulatory protein required for calcium mobilization from acidic organelles.30
333622372020LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient.8
333622372020LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient.8

Citation

Dessen P

LSM12 (LSM12 homolog)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68684/js/lib/css/template-nav.css