MED4 (mediator complex subunit 4)

2014-11-01  

Identity

HGNC
LOCATION
13q14.2
LOCUSID
ALIAS
ARC36,DRIP36,HSPC126,TRAP36,VDRIP
FUSION GENES

Other Information

Locus ID:

NCBI: 29079
MIM: 605718
HGNC: 17903
Ensembl: ENSG00000136146

Variants:

dbSNP: 29079
ClinVar: 29079
TCGA: ENSG00000136146
COSMIC: MED4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136146ENST00000258648Q9NPJ6
ENSG00000136146ENST00000258648A0A024RDY7
ENSG00000136146ENST00000378586Q9NPJ6
ENSG00000136146ENST00000417167Q5T911
ENSG00000136146ENST00000495013A0A087X0U0

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Thyroid hormone signaling pathwayKEGGhsa04919
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of white adipocyte differentiationREACTOMER-HSA-381340

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194111832009Staphylococcus aureus nasal carriage might be associated with vitamin D receptor polymorphisms in type 1 diabetes.13
248589102014The survival gene MED4 explains low penetrance retinoblastoma in patients with large RB1 deletion.7

Citation

Dessen P

MED4 (mediator complex subunit 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68882/med4