MPEG1 (macrophage expressed 1)

2014-11-01  

Identity

HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
IMD77,MPG1,MPS1,Mpg-1,P-2

Other Information

Locus ID:

NCBI: 219972
MIM: 610390
HGNC: 29619
Ensembl: ENSG00000197629

Variants:

dbSNP: 219972
ClinVar: 219972
TCGA: ENSG00000197629
COSMIC: MPEG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197629ENST00000361050Q2M385

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
336927802021Breaching the Bacterial Envelope: The Pivotal Role of Perforin-2 (MPEG1) Within Phagocytes.5
347301102021Intracellular Staphylococcus aureus triggers pyroptosis and contributes to inhibition of healing due to perforin-2 suppression.22
336927802021Breaching the Bacterial Envelope: The Pivotal Role of Perforin-2 (MPEG1) Within Phagocytes.5
347301102021Intracellular Staphylococcus aureus triggers pyroptosis and contributes to inhibition of healing due to perforin-2 suppression.22
328288202020Macrophage-specific protein perforin-2 is associated with poor neurological recovery and reduced survival after sudden cardiac arrest.0
328288202020Macrophage-specific protein perforin-2 is associated with poor neurological recovery and reduced survival after sudden cardiac arrest.0
287053752017Regulation of expression and trafficking of perforin-2 by LPS and TNF-α.9
287053752017Regulation of expression and trafficking of perforin-2 by LPS and TNF-α.9
263075492015Perforin-2/Mpeg1 and other pore-forming proteins throughout evolution.37
264187462015Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2.29
263075492015Perforin-2/Mpeg1 and other pore-forming proteins throughout evolution.37
264187462015Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2.29
237536252013Perforin-2 restricts growth of Chlamydia trachomatis in macrophages.29
237536252013Perforin-2 restricts growth of Chlamydia trachomatis in macrophages.29

Citation

Dessen P

MPEG1 (macrophage expressed 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70389/css/lib/favicon/favicon-32x32.png