NPS (neuropeptide S)

2014-11-01  

Identity

HGNC
NPS
LOCATION
10q26.2
LOCUSID
594857
ALIAS
-

Other Information

Locus ID:

NCBI: 594857
MIM: 609513
HGNC: 33940
Ensembl: ENSG00000214285

Variants:

dbSNP: 594857
ClinVar: 594857
TCGA: ENSG00000214285
COSMIC: NPS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214285ENST00000398023P0C0P6

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
382872312024Sphingosine 1-phosphate signaling axis mediates neuropeptide S-induced invasive phenotype of endometriotic cells.0
382872312024Sphingosine 1-phosphate signaling axis mediates neuropeptide S-induced invasive phenotype of endometriotic cells.0
335564452021Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality.6
342525862021Further refining the critical region of 10q26 microdeletion syndrome: A possible involvement of INSYN2 and NPS in the cognitive phenotype.1
335564452021Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality.6
342525862021Further refining the critical region of 10q26 microdeletion syndrome: A possible involvement of INSYN2 and NPS in the cognitive phenotype.1
313263752019Dopamine D(1) and D(2) receptors mediate neuropeptide S-induced antinociception in the mouse formalin test.5
313263752019Dopamine D(1) and D(2) receptors mediate neuropeptide S-induced antinociception in the mouse formalin test.5
284639952017Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma.6
284639952017Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma.6
231421102013Neuropeptide S stimulates human monocyte chemotaxis via NPS receptor activation.7
243861352013A single-nucleotide polymorphism of human neuropeptide s gene originated from Europe shows decreased bioactivity.4
231421102013Neuropeptide S stimulates human monocyte chemotaxis via NPS receptor activation.7
243861352013A single-nucleotide polymorphism of human neuropeptide s gene originated from Europe shows decreased bioactivity.4
204053302011Non-synonymous polymorphism in the neuropeptide S precursor gene and sleep apnea.2

Citation

Dessen P

NPS (neuropeptide S)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70950/gene-explorer/css/template-card.css