OTOS (otospiralin)

2014-11-01  

Identity

HGNC
OTOS
LOCATION
2q37.3
LOCUSID
150677
ALIAS
OTOSP

Other Information

Locus ID:

NCBI: 150677
MIM: 607877
HGNC: 22644
Ensembl: ENSG00000178602

Variants:

dbSNP: 150677
ClinVar: 150677
TCGA: ENSG00000178602
COSMIC: OTOS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178602ENST00000319460Q8NHW6
ENSG00000178602ENST00000391989Q8NHW6

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA445062NeoplasmsDiseaseClinicalAnnotationassociatedPD25410892, 31666714
PA449014cisplatinChemicalClinicalAnnotationassociatedPD25410892, 31666714

References

Pubmed IDYearTitleCitations
254108922014Genetic variation in Otos is associated with cisplatin-induced ototoxicity.0
254108922014Genetic variation in Otos is associated with cisplatin-induced ototoxicity.0
126874212003Gene structure, chromosomal localization, and mutation screening of the human gene for the inner ear protein otospiralin.1
126874212003Gene structure, chromosomal localization, and mutation screening of the human gene for the inner ear protein otospiralin.1

Citation

Dessen P

OTOS (otospiralin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71579/css/js/_common.js