PRPF18 (pre-mRNA processing factor 18)

2014-11-01  

Identity

HGNC
LOCATION
10p13
LOCUSID
ALIAS
PRP18,hPrp18
FUSION GENES

Other Information

Locus ID:

NCBI: 8559
MIM: 604993
HGNC: 17351
Ensembl: ENSG00000165630

Variants:

dbSNP: 8559
ClinVar: 8559
TCGA: ENSG00000165630
COSMIC: PRPF18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165630ENST00000320054Q5T9P8
ENSG00000165630ENST00000378572Q99633
ENSG00000165630ENST00000417658Q5T9P7

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
283002012017Identification of a novel locus associated with skin colour in African-admixed populations.7
278528612017Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity.6
222135622012Solution structure of the splicing factor motif of the human Prp18 protein.1

Citation

Dessen P

PRPF18 (pre-mRNA processing factor 18)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72250/prpf18