PRSS53 (serine protease 53)

2014-11-01  

Identity

HGNC
PRSS53
LOCATION
16p11.2
LOCUSID
339105
ALIAS
POL3S,UNQ308
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 339105
MIM: 610561
HGNC: 34407
Ensembl: ENSG00000151006

Variants:

dbSNP: 339105
ClinVar: 339105
TCGA: ENSG00000151006
COSMIC: PRSS53

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151006ENST00000280606Q2L4Q9

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA451906warfarinChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
165668202006Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain.8
165668202006Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain.8

Citation

Dessen P

PRSS53 (serine protease 53)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72316/teaching-explorer/deep-insight-explorer/css/lib/bootstrap.min.css