ATP6V0A1 (ATPase H+ transporting V0 subunit a1)

2003-06-01  

Identity

HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
ATP6N1,ATP6N1A,Stv1,VPP1,Vph1,a1
FUSION GENES

Other Information

Locus ID:

NCBI: 535
MIM: 192130
HGNC: 865
Ensembl: ENSG00000033627

Variants:

dbSNP: 535
ClinVar: 535
TCGA: ENSG00000033627
COSMIC: ATP6V0A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000033627ENST00000264649Q93050
ENSG00000033627ENST00000343619Q93050
ENSG00000033627ENST00000393829Q93050
ENSG00000033627ENST00000537728B7Z641
ENSG00000033627ENST00000544137F5H1T6
ENSG00000033627ENST00000585525B7Z2A9
ENSG00000033627ENST00000586201K7ERA6
ENSG00000033627ENST00000587510K7ERA0
ENSG00000033627ENST00000587824K7EM24
ENSG00000033627ENST00000588138K7ENA1
ENSG00000033627ENST00000588901K7EQW2
ENSG00000033627ENST00000589213K7ELZ6
ENSG00000033627ENST00000589727K7EPG4
ENSG00000033627ENST00000592324K7EN36

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Vibrio cholerae infectionKEGGko05110
Epithelial cell signaling in Helicobacter pylori infectionKEGGko05120
Oxidative phosphorylationKEGGhsa00190
Vibrio cholerae infectionKEGGhsa05110
Epithelial cell signaling in Helicobacter pylori infectionKEGGhsa05120
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Metabolic pathwaysKEGGhsa01100
Collecting duct acid secretionKEGGko04966
Collecting duct acid secretionKEGGhsa04966
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Rheumatoid arthritisKEGGko05323
Rheumatoid arthritisKEGGhsa05323
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Synaptic vesicle cycleKEGGko04721
Synaptic vesicle cycleKEGGhsa04721
V-type ATPase, eukaryotesKEGGhsa_M00160
V-type ATPase, eukaryotesKEGGM00160
ROS, RNS production in phagocytesREACTOMER-HSA-1222556
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Signaling by Insulin receptorREACTOMER-HSA-74752
Insulin receptor recyclingREACTOMER-HSA-77387
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Iron uptake and transportREACTOMER-HSA-917937
Transferrin endocytosis and recyclingREACTOMER-HSA-917977
Ion channel transportREACTOMER-HSA-983712
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
200389472011Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.101
240727072013The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.29
185050592008POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?17
227085442012Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum.12
215581232011A common genetic variant in the 3'-UTR of vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA motif to alter chromogranin A processing and hypertension risk.8

Citation

Dessen P

ATP6V0A1 (ATPase H+ transporting V0 subunit a1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/725/atp6v0a1