SFXN4 (sideroflexin 4)

2014-11-01  

Identity

HGNC
SFXN4
LOCATION
10q26.11
LOCUSID
119559
ALIAS
BCRM1,COXPD18,SLC56A4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 119559
MIM: 615564
HGNC: 16088
Ensembl: ENSG00000183605

Variants:

dbSNP: 119559
ClinVar: 119559
TCGA: ENSG00000183605
COSMIC: SFXN4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183605ENST00000355697Q6P4A7
ENSG00000183605ENST00000369131B1AMV7
ENSG00000183605ENST00000419372B1AMV8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377864392023Comprehensive Analysis of Sideroflexin 4 in Hepatocellular Carcinoma by Bioinformatics and Experiments.0
377864392023Comprehensive Analysis of Sideroflexin 4 in Hepatocellular Carcinoma by Bioinformatics and Experiments.0
353336552022Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module.10
353336552022Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module.10
310598222019[Prenatal onset of mitochondrial disease is associated with sideroflexin 4 deficiency].5
318731202019Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.21
310598222019[Prenatal onset of mitochondrial disease is associated with sideroflexin 4 deficiency].5
318731202019Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.21
241196842013Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.35
241196842013Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.35
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83

Citation

Dessen P

SFXN4 (sideroflexin 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73176/gene-fusions/case-report-explorer/js/web-card-_common.js