SLC17A6 (solute carrier family 17 member 6)

2014-11-01 Affiliation

Identity

HGNC

SLC17A6

LOCATION

11p14.3

LOCUSID

57084

ALIAS

DNPI,VGLUT2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 57084
MIM: 607563
HGNC: 16703
Ensembl: ENSG00000091664

Variants:

dbSNP: 57084
ClinVar: 57084
TCGA: ENSG00000091664
COSMIC: SLC17A6

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000091664	ENST00000263160	Q9P2U8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Glutamatergic synapse	KEGG	ko04724
Glutamatergic synapse	KEGG	hsa04724
Synaptic vesicle cycle	KEGG	ko04721
Synaptic vesicle cycle	KEGG	hsa04721
Retrograde endocannabinoid signaling	KEGG	hsa04723
Retrograde endocannabinoid signaling	KEGG	ko04723
Nicotine addiction	KEGG	hsa05033
Nicotine addiction	KEGG	ko05033
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
SLC-mediated transmembrane transport	REACTOME	R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME	R-HSA-425393
Organic anion transporters	REACTOME	R-HSA-428643

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34994539	2022	Roles of VGLUT2 and Dopamine/Glutamate Co-Transmission in Selective Vulnerability to Dopamine Neurodegeneration.	5
34994539	2022	Roles of VGLUT2 and Dopamine/Glutamate Co-Transmission in Selective Vulnerability to Dopamine Neurodegeneration.	5
30203849	2018	Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons.	21
30203849	2018	Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons.	21
26386900	2015	Uncovering the role of the nucleus accumbens in schizophrenia: A postmortem analysis of tyrosine hydroxylase and vesicular glutamate transporters.	16
26439639	2015	Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors.	122
26386900	2015	Uncovering the role of the nucleus accumbens in schizophrenia: A postmortem analysis of tyrosine hydroxylase and vesicular glutamate transporters.	16
26439639	2015	Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors.	122
25319687	2014	Role of glutamatergic projections from ventral tegmental area to lateral habenula in aversive conditioning.	109
25319702	2014	Multimodal use of calcitonin gene-related peptide and substance P in itch and acute pain uncovered by the elimination of vesicular glutamate transporter 2 from transient receptor potential cation channel subfamily V member 1 neurons.	20
25319687	2014	Role of glutamatergic projections from ventral tegmental area to lateral habenula in aversive conditioning.	109
25319702	2014	Multimodal use of calcitonin gene-related peptide and substance P in itch and acute pain uncovered by the elimination of vesicular glutamate transporter 2 from transient receptor potential cation channel subfamily V member 1 neurons.	20
22684983	2013	Distribution of vesicular glutamate transporter 2 (VGluT2) in the primary visual cortex of the macaque and human.	22
22684983	2013	Distribution of vesicular glutamate transporter 2 (VGluT2) in the primary visual cortex of the macaque and human.	22
22510271	2012	Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons.	10

Citation

Dessen P

SLC17A6 (solute carrier family 17 member 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73304/gene-explorer/css/card-gene.css