BAG4 (BAG cochaperone 4)

2003-06-01  

Identity

HGNC
LOCATION
8p11.23
LOCUSID
ALIAS
BAG-4,SODD
FUSION GENES

Other Information

Locus ID:

NCBI: 9530
MIM: 603884
HGNC: 940
Ensembl: ENSG00000156735

Variants:

dbSNP: 9530
ClinVar: 9530
TCGA: ENSG00000156735
COSMIC: BAG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156735ENST00000287322O95429
ENSG00000156735ENST00000432471O95429
ENSG00000156735ENST00000521311H0YBT1

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
TNF signaling pathwayKEGGhsa04668
TNF signaling pathwayKEGGko04668
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Signaling by FGFR in diseaseREACTOMER-HSA-1226099
Signaling by FGFR1 in diseaseREACTOMER-HSA-5655302
FGFR1 mutant receptor activationREACTOMER-HSA-1839124
Signal TransductionREACTOMER-HSA-162582
Death Receptor SignallingREACTOMER-HSA-73887
TNF signalingREACTOMER-HSA-75893
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453
Signaling by plasma membrane FGFR1 fusionsREACTOMER-HSA-8853336

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371075872023SODD Promotes Lung Cancer Tumorigenesis by Activating the PDK1/AKT and RAF/MEK/ERK Signaling.1
371075872023SODD Promotes Lung Cancer Tumorigenesis by Activating the PDK1/AKT and RAF/MEK/ERK Signaling.1
344195012021Bcl2-associated athanogene 4 promotes the invasion and metastasis of gastric cancer cells by activating the PI3K/AKT/NF-κB/ZEB1 axis.11
344195012021Bcl2-associated athanogene 4 promotes the invasion and metastasis of gastric cancer cells by activating the PI3K/AKT/NF-κB/ZEB1 axis.11
277567722017Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett's Associated Esophageal Adenocarcinoma Cells.3
290674452017Bcl‑2 associated athanogene 4 promotes proliferation, migration and invasion of gastric cancer cells.0
277567722017Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett's Associated Esophageal Adenocarcinoma Cells.3
290674452017Bcl‑2 associated athanogene 4 promotes proliferation, migration and invasion of gastric cancer cells.0
247374272014Significance of SODD expression in childhood acute lymphoblastic leukemia and its influence on chemotherapy.1
247374272014Significance of SODD expression in childhood acute lymphoblastic leukemia and its influence on chemotherapy.1
231908982013MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD).27
231908982013MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD).27
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
208555362010Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.22
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15

Citation

Dessen P

BAG4 (BAG cochaperone 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/743/img/js/web-card-gene.js