USE1 (unconventional SNARE in the ER 1)

ARTICLE CONTENTS

To the top

Other actions (beta)

Download as PDF

USE1 (unconventional SNARE in the ER 1)

2014-11-01 Affiliation

Identity

HGNC

LOCATION

19p13.11

LOCUSID

ALIAS

D12,MDS032,P31,SLT1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 55850
MIM: 610675
HGNC: 30882
Ensembl: ENSG00000053501

Variants:

dbSNP: 55850
ClinVar: 55850
TCGA: ENSG00000053501
COSMIC: USE1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000053501	ENST00000263897	Q9NZ43
ENSG00000053501	ENST00000445667	G8JLK1
ENSG00000053501	ENST00000593597	M0QYT5
ENSG00000053501	ENST00000594724	M0QZZ6
ENSG00000053501	ENST00000595101	Q9NZ43
ENSG00000053501	ENST00000596136	Q9NZ43
ENSG00000053501	ENST00000600970	M0QZE0
ENSG00000053501	ENST00000601662	M0QZZ6

Expression (GTEx)

0

5

10

15

20

25

30

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
SNARE interactions in vesicular transport	KEGG	ko04130
SNARE interactions in vesicular transport	KEGG	hsa04130
Vesicle-mediated transport	REACTOME	R-HSA-5653656
Membrane Trafficking	REACTOME	R-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER traffic	REACTOME	R-HSA-6811442
Golgi-to-ER retrograde transport	REACTOME	R-HSA-8856688
COPI-dependent Golgi-to-ER retrograde traffic	REACTOME	R-HSA-6811434

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
37604583	2023	Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions.	1
37604583	2023	Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions.	1
27569286	2016	LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6.	6
27569286	2016	LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6.	6
24528925	2014	Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1.	16
25184340	2014	Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment.	11
24528925	2014	Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1.	16
25184340	2014	Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment.	11
20975683	2010	USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.	42
20975683	2010	USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.	42
19369418	2009	Identification of the neuroblastoma-amplified gene product as a component of the syntaxin 18 complex implicated in Golgi-to-endoplasmic reticulum retrograde transport.	56
19369418	2009	Identification of the neuroblastoma-amplified gene product as a component of the syntaxin 18 complex implicated in Golgi-to-endoplasmic reticulum retrograde transport.	56

Citation

Dessen P

USE1 (unconventional SNARE in the ER 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75517/css/haematological-explorer/js/lib/jquery-3.5.1.min.js