ZC3H3 (zinc finger CCCH-type containing 3)

2014-11-01  

Identity

HGNC
ZC3H3
LOCATION
8q24.3
LOCUSID
23144
ALIAS
SMICL,ZC3HDC3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23144
MIM: 618640
HGNC: 28972
Ensembl: ENSG00000014164

Variants:

dbSNP: 23144
ClinVar: 23144
TCGA: ENSG00000014164
COSMIC: ZC3H3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000014164ENST00000262577Q8IXZ2
ENSG00000014164ENST00000528401H0YEY2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
319501732020The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.1

Citation

Dessen P

ZC3H3 (zinc finger CCCH-type containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75884/zc3h3-(zinc-finger-ccch-type-containing-3)