BCL2L10 (BCL2 like 10)

2003-02-01  

Identity

HGNC
BCL2L10
LOCATION
15q21.2
LOCUSID
10017
ALIAS
BCL-B,Boo,Diva,bcl2-L-10

Other Information

Locus ID:

NCBI: 10017
MIM: 606910
HGNC: 993
Ensembl: ENSG00000137875

Variants:

dbSNP: 10017
ClinVar: 10017
TCGA: ENSG00000137875
COSMIC: BCL2L10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137875ENST00000260442Q9HD36
ENSG00000137875ENST00000561198H0YMD5

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373914382023Nrh L11R single nucleotide polymorphism, a new prediction biomarker in breast cancer, impacts endoplasmic reticulum-dependent Ca(2+) traffic and response to neoadjuvant chemotherapy.2
378994532023Bcl-B: an "unknown" protein of the Bcl-2 family.1
373914382023Nrh L11R single nucleotide polymorphism, a new prediction biomarker in breast cancer, impacts endoplasmic reticulum-dependent Ca(2+) traffic and response to neoadjuvant chemotherapy.2
378994532023Bcl-B: an "unknown" protein of the Bcl-2 family.1
336497942021Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1.3
336497942021Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1.3
318942742020Bcl2l10 mediates the proliferation, invasion and migration of ovarian cancer cells.6
318942742020Bcl2l10 mediates the proliferation, invasion and migration of ovarian cancer cells.6
293301432018Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10.22
293301432018Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10.22
272606552017A balanced translocation disrupting BCL2L10 and PNLDC1 segregates with affective psychosis.5
277705802017BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo.10
282598202017BCLB, methylated in hepatocellular carcinoma, is a starvation stress sensor that induces apoptosis and autophagy through the AMPK-mTOR signaling cascade.22
285147582017BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia.10
272606552017A balanced translocation disrupting BCL2L10 and PNLDC1 segregates with affective psychosis.5

Citation

Dessen P

BCL2L10 (BCL2 like 10)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/771/img/js/_common.js