BMP15 (bone morphogenetic protein 15)

2004-02-01  

Identity

HGNC
BMP15
LOCATION
Xp11.22
LOCUSID
9210
ALIAS
GDF9B,ODG2,POF4

Other Information

Locus ID:

NCBI: 9210
MIM: 300247
HGNC: 1068
Ensembl: ENSG00000130385

Variants:

dbSNP: 9210
ClinVar: 9210
TCGA: ENSG00000130385
COSMIC: BMP15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130385ENST00000252677O95972

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Ovarian steroidogenesisKEGGhsa04913
Ovarian steroidogenesisKEGGko04913

References

Pubmed IDYearTitleCitations
363729882023Serum GDF9 and BMP15 as potential markers of ovarian function in women with and without polycystic ovary syndrome.5
366890452023Decreased GDF9 and BMP15 in follicle fluid and granulosa cells and outcomes of IVF-ET among young patients with low prognosis.2
363729882023Serum GDF9 and BMP15 as potential markers of ovarian function in women with and without polycystic ovary syndrome.5
366890452023Decreased GDF9 and BMP15 in follicle fluid and granulosa cells and outcomes of IVF-ET among young patients with low prognosis.2
352324442022Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency.5
358619202022Identification of novel biallelic variants in BMP15 in two siblings with premature ovarian insufficiency.2
352324442022Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency.5
358619202022Identification of novel biallelic variants in BMP15 in two siblings with premature ovarian insufficiency.2
329974252021Bone morphogenetic protein 15 induces differentiation of mesenchymal stem cells derived from human follicular fluid to oocyte-like cell.11
333974082021Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders.10
341875392021Characterization of a novel mutation V136L in bone morphogenetic protein 15 identified in a woman affected by POI.10
329974252021Bone morphogenetic protein 15 induces differentiation of mesenchymal stem cells derived from human follicular fluid to oocyte-like cell.11
333974082021Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders.10
341875392021Characterization of a novel mutation V136L in bone morphogenetic protein 15 identified in a woman affected by POI.10
319571782020Fundamental role of BMP15 in human ovarian folliculogenesis revealed by null and missense mutations associated with primary ovarian insufficiency.10

Citation

Dessen P

BMP15 (bone morphogenetic protein 15)

Atlas Genet Cytogenet Oncol Haematol. 2004-02-01

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