BMP8B (bone morphogenetic protein 8b)

2003-05-01  

Identity

HGNC
BMP8B
LOCATION
1p34.2
LOCUSID
656
ALIAS
BMP8,OP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 656
MIM: 602284
HGNC: 1075
Ensembl: ENSG00000116985

Variants:

dbSNP: 656
ClinVar: 656
TCGA: ENSG00000116985
COSMIC: BMP8B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116985ENST00000372827P34820

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
TGF-beta signaling pathwayKEGGko04350
TGF-beta signaling pathwayKEGGhsa04350
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
BMP signalingKEGGhsa_M00679
BMP signalingKEGGM00679

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
163148332006Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas.30
150637622004Genetic variations in humans associated with differences in the course of hepatitis C.16
90709441997The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4.8
251760582014BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer.6
277485382017BMP8B Is a Tumor Suppressor Gene Regulated by Histone Acetylation in Gastric Cancer.3
310966382019Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro.3
240761312013Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle.1

Citation

Dessen P

BMP8B (bone morphogenetic protein 8b)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/815/bmp8b-(bone-morphogenetic-protein-8b)