BNIP2 (BCL2 interacting protein 2)

2003-11-01  

Identity

HGNC
LOCATION
15q22.2
LOCUSID
ALIAS
BNIP-2,NIP2
FUSION GENES

Other Information

Locus ID:

NCBI: 663
MIM: 603292
HGNC: 1083
Ensembl: ENSG00000140299

Variants:

dbSNP: 663
ClinVar: 663
TCGA: ENSG00000140299
COSMIC: BNIP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140299ENST00000267859J3KN59
ENSG00000140299ENST00000415213Q12982
ENSG00000140299ENST00000439052H7C096
ENSG00000140299ENST00000448414H7C142
ENSG00000140299ENST00000607373Q12982
ENSG00000140299ENST00000612191J3KN59

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
MyogenesisREACTOMER-HSA-525793
CDO in myogenesisREACTOMER-HSA-375170

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
359754202022BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation.4
359754202022BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation.4
327891682020BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation.13
327891682020BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation.13
253785812015KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation.7
254724452015BNIP-2 binds phosphatidylserine, localizes to vesicles, and is transported by kinesin-1.1
253785812015KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation.7
254724452015BNIP-2 binds phosphatidylserine, localizes to vesicles, and is transported by kinesin-1.1
211300872011SIRT1 deficiency attenuates MPP+-induced apoptosis in dopaminergic cells.10
211300872011SIRT1 deficiency attenuates MPP+-induced apoptosis in dopaminergic cells.10
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
207045642010Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.4
208555362010Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.22
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
207045642010Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.4

Citation

Dessen P

BNIP2 (BCL2 interacting protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/821/favicon/js/lib/all.min.js