BTG4 (BTG anti-proliferation factor 4)

2003-02-01  

Identity

HGNC
BTG4
LOCATION
11q23.1
LOCUSID
54766
ALIAS
APRO3,OOMD8,PC3B

Other Information

Locus ID:

NCBI: 54766
MIM: 605673
HGNC: 13862
Ensembl: ENSG00000137707

Variants:

dbSNP: 54766
ClinVar: 54766
TCGA: ENSG00000137707
COSMIC: BTG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137707ENST00000356018Q9NY30
ENSG00000137707ENST00000456861E9PRM5
ENSG00000137707ENST00000525791Q9NY30

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018

References

Pubmed IDYearTitleCitations
185196712008Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.216
203099402011A potentially functional polymorphism in the promoter region of miR-34b/c is associated with an increased risk for primary hepatocellular carcinoma.65
156724092005Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia.12
195761782009Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer.9

Citation

Dessen P

BTG4 (BTG anti-proliferation factor 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/850/btg4-(btg-anti-proliferation-factor-4)