C1QTNF6 (C1q and TNF related 6)

2003-06-01  

Identity

HGNC
C1QTNF6
LOCATION
22q12.3
LOCUSID
114904
ALIAS
CTFP6,CTRP6,ZACRP6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 114904
MIM: 614910
HGNC: 14343
Ensembl: ENSG00000133466

Variants:

dbSNP: 114904
ClinVar: 114904
TCGA: ENSG00000133466
COSMIC: C1QTNF6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133466ENST00000337843Q9BXI9
ENSG00000133466ENST00000337843A0A024R1J0
ENSG00000133466ENST00000397110Q9BXI9
ENSG00000133466ENST00000397110A0A024R1J0
ENSG00000133466ENST00000434784F8WC87

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387509212024Down regulation of C1q tumor necrosis factor-related protein 6 is associated with increased risk of breast cancer.0
387509212024Down regulation of C1q tumor necrosis factor-related protein 6 is associated with increased risk of breast cancer.0
363481392023MiR-29c-3p/C1QTNF6 Restrains the Angiogenesis and Cell Proliferation, Migration and Invasion in Head and Neck Squamous Cell Carcinoma.0
380847022023CTRP6 protects against ferroptosis to drive lung cancer progression and metastasis by destabilizing SOCS2 and augmenting the xCT/GPX4 pathway.1
363481392023MiR-29c-3p/C1QTNF6 Restrains the Angiogenesis and Cell Proliferation, Migration and Invasion in Head and Neck Squamous Cell Carcinoma.0
380847022023CTRP6 protects against ferroptosis to drive lung cancer progression and metastasis by destabilizing SOCS2 and augmenting the xCT/GPX4 pathway.1
349647052022C1q/tumor necrosis factor related protein 6 (CTRP6) regulates the phenotypes of high glucose-induced gestational trophoblast cells via peroxisome proliferator-activated receptor gamma (PPARγ) signaling.5
353970572022Potential participation of CTRP6, a complement regulator, in the pathology of age related macular degeneration.1
349647052022C1q/tumor necrosis factor related protein 6 (CTRP6) regulates the phenotypes of high glucose-induced gestational trophoblast cells via peroxisome proliferator-activated receptor gamma (PPARγ) signaling.5
353970572022Potential participation of CTRP6, a complement regulator, in the pathology of age related macular degeneration.1
332458992021Role of the CTRP6/AMPK pathway in kidney fibrosis through the promotion of fatty acid oxidation.9
332693762021C1QTNF6 regulates cell proliferation and apoptosis of NSCLC in vitro and in vivo.11
344692062021Adipocyte factor CTRP6 inhibits homocysteine-induced proliferation, migration, and dedifferentiation of vascular smooth muscle cells through PPARγ/NLRP3.4
346327972021CTRP6 rapidly responds to acute nutritional changes, regulating adipose tissue expansion and inflammation in mice.9
332458992021Role of the CTRP6/AMPK pathway in kidney fibrosis through the promotion of fatty acid oxidation.9

Citation

Dessen P

C1QTNF6 (C1q and TNF related 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/878/teaching-explorer/gene-fusions-explorer/css/lib/dataTables.bootstrap.min.css