SDF4 (stromal cell derived factor 4)

2003-12-01  

Identity

HGNC
SDF4
LOCATION
1p36.33
LOCUSID
51150
ALIAS
Cab45,SDF-4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51150
MIM: 614282
HGNC: 24188
Ensembl: ENSG00000078808

Variants:

dbSNP: 51150
ClinVar: 51150
TCGA: ENSG00000078808
COSMIC: SDF4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078808ENST00000403997H0Y3T6
ENSG00000078808ENST00000465727G3V1E2
ENSG00000078808ENST00000660930Q9BRK5
ENSG00000078808ENST00000660930A0A024R0A9

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
363989802023Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning.1
366063222023LINC00173 facilitates tumor progression by stimulating RAB1B-mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma.3
363989802023Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning.1
366063222023LINC00173 facilitates tumor progression by stimulating RAB1B-mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma.3
343268342021SDF4 Is a Prognostic Factor for 28-Days Mortality in Patients With Sepsis via Negatively Regulating ER Stress.5
343268342021SDF4 Is a Prognostic Factor for 28-Days Mortality in Patients With Sepsis via Negatively Regulating ER Stress.5
324226532020Fam20C regulates protein secretion by Cab45 phosphorylation.11
324226532020Fam20C regulates protein secretion by Cab45 phosphorylation.11
257722372016Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling.16
271382532016Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network.31
257722372016Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling.16
271382532016Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network.31
248100552014Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP.36
248100552014Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP.36
255098782013[The effects of simulated microgravity on the pattern of gene expression in human bone marrow mesenchymal stem cells under osteogenic differentiation].3

Citation

Dessen P

SDF4 (stromal cell derived factor 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/899/js/lib/favicon/favicon-32x32.png