CAMK1 (calcium/calmodulin dependent protein kinase I)

2003-11-01 Affiliation

Identity

HGNC

CAMK1

LOCATION

3p25.3

LOCUSID

8536

ALIAS

CAMKI

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8536
MIM: 604998
HGNC: 1459
Ensembl: ENSG00000134072

Variants:

dbSNP: 8536
ClinVar: 8536
TCGA: ENSG00000134072
COSMIC: CAMK1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000134072	ENST00000256460	Q14012
ENSG00000134072	ENST00000256460	B0YIY3
ENSG00000134072	ENST00000397277	F8W6S9
ENSG00000134072	ENST00000411972	C9JES6
ENSG00000134072	ENST00000421120	H7C071

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Oxytocin signaling pathway	KEGG	hsa04921
Oxytocin signaling pathway	KEGG	ko04921
Aldosterone synthesis and secretion	KEGG	hsa04925
Aldosterone synthesis and secretion	KEGG	ko04925

Protein levels (Protein atlas)

Not detected

Low

Medium

High

PharmGKB

Entity ID	Name	Type	Evidence	Association
PA248	NFKB1	Gene	Pathway	associated
PA27749	ELK1	Gene	Pathway	associated
PA28212	FOS	Gene	Pathway	associated
PA296	RELA	Gene	Pathway	associated
PA30006	JUN	Gene	Pathway	associated
PA31353	MYC	Gene	Pathway	associated
PA31600	NFKB2	Gene	Pathway	associated
PA337	STAT3	Gene	Pathway	associated
PA338	STAT5A	Gene	Pathway	associated
PA36042	SP1	Gene	Pathway	associated
PA36183	STAT1	Gene	Pathway	associated
PA36184	STAT2	Gene	Pathway	associated
PA36185	STAT4	Gene	Pathway	associated
PA36186	STAT5B	Gene	Pathway	associated

References

Pubmed ID	Year	Title	Citations
33342045	2021	Expression of CAMK1 and its association with clinicopathologic characteristics in pancreatic cancer.	18
33342045	2021	Expression of CAMK1 and its association with clinicopathologic characteristics in pancreatic cancer.	18
27907007	2016	Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy.	3
27907007	2016	Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy.	3
26466644	2015	The immunomodulatory effects of barettin and involvement of the kinases CAMK1α and RIPK2.	3
26466644	2015	The immunomodulatory effects of barettin and involvement of the kinases CAMK1α and RIPK2.	3
24461366	2014	Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease.	14
24825433	2014	CAMK1 phosphoinositide signal-mediated protein sorting and transport network in human hepatocellular carcinoma (HCC) by biocomputation.	8
24841198	2014	Interaction between salt-inducible kinase 2 and protein phosphatase 2A regulates the activity of calcium/calmodulin-dependent protein kinase I and protein phosphatase methylesterase-1.	11
24461366	2014	Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease.	14
24825433	2014	CAMK1 phosphoinositide signal-mediated protein sorting and transport network in human hepatocellular carcinoma (HCC) by biocomputation.	8
24841198	2014	Interaction between salt-inducible kinase 2 and protein phosphatase 2A regulates the activity of calcium/calmodulin-dependent protein kinase I and protein phosphatase methylesterase-1.	11
23707388	2013	Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.	10
23707388	2013	Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.	10
23028635	2012	Crystal structures of human CaMKIα reveal insights into the regulation mechanism of CaMKI.	7

Citation

Dessen P

CAMK1 (calcium/calmodulin dependent protein kinase I)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/905/gene-explorer/tumors-explorer/favicon/favicon-32x32.png