CD72 (CD72 molecule)

2003-11-01  

Identity

HGNC
CD72
LOCATION
9p13.3
LOCUSID
971
ALIAS
CD72b,LYB2

Other Information

Locus ID:

NCBI: 971
MIM: 107272
HGNC: 1696
Ensembl: ENSG00000137101

Variants:

dbSNP: 971
ClinVar: 971
TCGA: ENSG00000137101
COSMIC: CD72

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137101ENST00000259633P21854
ENSG00000137101ENST00000259633Q5TLG3
ENSG00000137101ENST00000378430Q5T4Q7
ENSG00000137101ENST00000378431Q5T4Q8
ENSG00000137101ENST00000396757P21854
ENSG00000137101ENST00000612238A0A087X0Y7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
B cell receptor signaling pathwayKEGGko04662
B cell receptor signaling pathwayKEGGhsa04662
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Semaphorin interactionsREACTOMER-HSA-373755
Other semaphorin interactionsREACTOMER-HSA-416700

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
364702092023CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus.3
378763422023CD72 is a pan-tumor antigen associated to pediatric acute leukemia.0
379805412023CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma.0
364702092023CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus.3
378763422023CD72 is a pan-tumor antigen associated to pediatric acute leukemia.0
379805412023CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma.0
363264552022Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion.0
363264552022Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion.0
323068932020A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren's syndrome.5
327005982020CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study.5
323068932020A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren's syndrome.5
327005982020CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study.5
282226232017Interferon-α-induced CD100 on naïve CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.3
282226232017Interferon-α-induced CD100 on naïve CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.3
268836812016Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis.6

Citation

Dessen P

CD72 (CD72 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/990/gene-fusions-explorer/js/lib/zoomerang.js