t(5;19)(q35;p13) NPM1/TYK2

2018-01-01   Jean-Loup Huret  , Philippe Dessen  

Clinics and Pathology

Disease

Anaplastic large cell lymphoma, cutaneous type|Subcutaneous panniculitis-like T-cell lymphoma

Genes Involved and Proteins

Gene name
NPM1
Location
5q35.1
Gene name
TYK2
Location
19p13.2

Highly cited references

Pubmed IDYearTitleCitations
253491762014A novel recurrent NPM1-TYK2 gene fusion in cutaneous CD30-positive lymphoproliferative disorders.36
291579732018When the good go bad: Mutant NPM1 in acute myeloid leukemia.35
350429702022Functional characterization of NPM1-TYK2 fusion oncogene.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
253491762014A novel recurrent NPM1-TYK2 gene fusion in cutaneous CD30-positive lymphoproliferative disorders.Velusamy T et al

Summary

Fusion gene

NPM1/TYK2 NPM1 (5q35.1) TYK2 (19p13.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(5;19)(q35;p13) NPM1/TYK2

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3023/img/css/teaching-explorer/js/lib/zoomerang.js