t(6;9)(q26;q21) QKI/NTRK2

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

QKI

Location

6q26

Gene name

NTRK2

Location

9q21.33

Highly cited references

Pubmed IDYearTitleCitations
274028152017Tyrosine receptor kinase B is a drug target in astrocytomas.15
343636822021Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation.1

Bibliography

Pubmed IDLast YearTitleAuthors
238175722013Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.Jones DT et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(6;9)(q26;q21) QKI/NTRK2

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/107358/t(6;9)(q26;q21)-qki-ntrk2