ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase)

2016-01-01  

Identity

HGNC
LOCATION
12p11.21
LOCUSID
ALIAS
C12orf72,ETFB-KMT,METTL20
FUSION GENES

Other Information

Locus ID:

NCBI: 254013
MIM: 615256
HGNC: 28739
Ensembl: ENSG00000139160

Variants:

dbSNP: 254013
ClinVar: 254013
TCGA: ENSG00000139160
COSMIC: ETFBKMT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139160ENST00000357721Q8IXQ9
ENSG00000139160ENST00000395763Q8IXQ9
ENSG00000139160ENST00000412352Q8IXQ9
ENSG00000139160ENST00000538391G5EA40
ENSG00000139160ENST00000538463Q8IXQ9
ENSG00000139160ENST00000539633F5H481

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Protein methylationREACTOMER-HSA-8876725

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
229488202012Lysine methylation of VCP by a member of a novel human protein methyltransferase family.51
254167812015Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity.23
250232812014Human METTL20 methylates lysine residues adjacent to the recognition loop of the electron transfer flavoprotein in mitochondria.0
293522212018Role of METTL20 in regulating β-oxidation and heat production in mice under fasting or ketogenic conditions.0

Citation

Dessen P

ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/77830/etfbkmt