Identity
HGNC
LOCATION
4q32.1
LOCUSID
ALIAS
GC-S-alpha-1,GC-SA3,GCS-alpha-3,GUC1A3,GUCA3,GUCSA3,GUCY1A3,MYMY6
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2982
MIM: 139396
HGNC: 4685
Ensembl: ENSG00000164116
Variants:
dbSNP: 2982
ClinVar: 2982
TCGA: ENSG00000164116
COSMIC: GUCY1A1
RNA/Proteins
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36941667 | 2023 | Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy. | 1 |
| 36941667 | 2023 | Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy. | 1 |
| 33430449 | 2021 | Inflammation in the Human Periodontium Induces Downregulation of the α(1)- and β(1)-Subunits of the sGC in Cementoclasts. | 2 |
| 33571505 | 2021 | Higher susceptibility to heme oxidation and lower protein stability of the rare α(1)C517Yβ(1) sGC variant associated with moyamoya syndrome. | 6 |
| 34535643 | 2021 | Activation mechanism of human soluble guanylate cyclase by stimulators and activators. | 20 |
| 33430449 | 2021 | Inflammation in the Human Periodontium Induces Downregulation of the α(1)- and β(1)-Subunits of the sGC in Cementoclasts. | 2 |
| 33571505 | 2021 | Higher susceptibility to heme oxidation and lower protein stability of the rare α(1)C517Yβ(1) sGC variant associated with moyamoya syndrome. | 6 |
| 34535643 | 2021 | Activation mechanism of human soluble guanylate cyclase by stimulators and activators. | 20 |
| 30597209 | 2019 | Differential expression of alternative transcripts of soluble guanylyl cyclase, GYCY1a3 and GUCY1b3 genes, in the malignant and benign breast tumors. | 5 |
| 30768153 | 2019 | Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention. | 6 |
| 31228190 | 2019 | Genetic variation at the coronary artery disease risk locus GUCY1A3 modifies cardiovascular disease prevention effects of aspirin. | 12 |
| 31616026 | 2019 | Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines. | 5 |
| 31645439 | 2019 | Synergistic mutations in soluble guanylyl cyclase (sGC) reveal a key role for interfacial regions in the sGC activation mechanism. | 6 |
| 31883534 | 2019 | Associations between GUCY1A3 genetic polymorphisms and large artery atherosclerotic stroke risk in Chinese Han population: a case-control study. | 2 |
| 30597209 | 2019 | Differential expression of alternative transcripts of soluble guanylyl cyclase, GYCY1a3 and GUCY1b3 genes, in the malignant and benign breast tumors. | 5 |
Citation
Dessen P
GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57292/gucy1a1
