t(6;11)(p21;q13) SRF/RELA

0000-00-00   Jean-Loup Huret  , Philippe Dessen  

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

SRF

Location

6p21.1

Gene name

RELA

Location

11q13.1

Highly cited references

Pubmed IDYearTitleCitations
396344172024Novel bioinformatic approaches show the role of driver genes in the progression of cervical cancer: An in-silico study.94
314789432020Novel SRF-ICA1L Fusions in Cellular Myoid Neoplasms With Potential For Malignant Behavior.21
282488152017Recurrent SRF-RELA Fusions Define a Novel Subset of Cellular Myofibroma/Myopericytoma: A Potential Diagnostic Pitfall With Sarcomas With Myogenic Differentiation.17
385245242024Misdiagnosis of synovial sarcoma - cellular myofibroma with SRF-RELA gene fusion: A case report.15
317386352021Myofibromatosis.0
330215232020SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors.0
358521782022Uterine tumours with myogenic differentiation harbouring SRF::RELA fusions.0
317051902020What is new in pericytomatous, myoid, and myofibroblastic tumors?0
325293512021Genetic variant of SRF-rearranged myofibroma with a misleading nuclear expression of STAT6 and STAT6 involvement as 3' fusion partner.0
381787492024[SRF-rearranged cellular perivascular myoid tumor: a clinicopathological analysis of two cases].0

Article Bibliography

Pubmed IDLast YearTitleAuthors
282488152017Recurrent SRF-RELA Fusions Define a Novel Subset of Cellular Myofibroma/Myopericytoma: A Potential Diagnostic Pitfall With Sarcomas With Myogenic Differentiation.Antonescu CR et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(6;11)(p21;q13) SRF/RELA

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/106866/t(6;11)(p21;q13)-srf-rela