t(1;2)(p13;q37) COL6A3::CSF1

Genes involved

COL6A3 (2q37.3)

CSF1 (1p13.3)

Oncogenic mechanisms

overexpression of CSF1

Tumor type

Pigmented villonodular synovitis

tenosynovial giant cell tumors

Highly cited references

Pubmed IDYearTitleCitations
179182572008Molecular identification of COL6A3-CSF1 fusion transcripts in tenosynovial giant cell tumors.0
314694682020Detection of CSF1 rearrangements deleting the 3' UTR in tenosynovial giant cell tumors.0
328863062021Establishment and characterization of a novel cell line, NCC-TGCT1-C1, derived from a patient with tenosynovial giant cell tumor.0
188294812008Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation.0
317713682020Tenosynovial Giant Cell Tumor, Localized Type With Extensive Chondroid Metaplasia: A Case Report With Immunohistochemical and Molecular Genetic Analysis.0

Bibliography

Pubmed IDPublication YearTitleAuthors
164071112006A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells.West RB, et al
179182572008Molecular identification of COL6A3-CSF1 fusion transcripts in tenosynovial giant cell tumors.Möller E, et al