t(4;9)(q31;q34) GAB1::ABL1
Oncogenic mechanisms
activation of ABL kinase
Tumor type
Soft tissue angiofibroma
soft tissue perineurioma
solitary fibrous tumor
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32859628 | 2020 | Recurrent Fusion of the GRB2 Associated Binding Protein 1 (GAB1) Gene With ABL Proto-oncogene 1 (ABL1) in Benign Pediatric Soft Tissue Tumors. | 67 |
| 36744864 | 2023 | GAB1::ABL1 fusions define a distinctive soft tissue neoplasm, with variable perineurial differentiation, and a predilection for children and young adults. | 0 |
| 34036664 | 2021 | GAB1-ABL1 fusions in tumors that have histologic overlap with NTRK-rearranged spindle cell tumors. | 0 |
| 39304199 | 2025 | Emerging fusion-associated mesenchymal tumours: a tabular guide and appraisal of five 'novel' entities. | 0 |
| 28639284 | 2017 | Soft tissue angiofibroma: Clinicopathologic, immunohistochemical and molecular analysis of 14 cases. | 0 |
| 36860189 | 2023 | Clinicopathologic and genetic characterization of angiofibroma of soft tissue: a study of 12 cases including two cases with AHRR::NCOA3 gene fusion. | 0 |
Bibliography
| Pubmed ID | Publication Year | Title | Authors |
|---|---|---|---|
| 28639284 | 2017 | Soft tissue angiofibroma: Clinicopathologic, immunohistochemical and molecular analysis of 14 cases. | Bekers EM, et al |
| 32859628 | 2020 | Recurrent Fusion of the GRB2 Associated Binding Protein 1 (GAB1) Gene With ABL Proto-oncogene 1 (ABL1) in Benign Pediatric Soft Tissue Tumors. | Panagopoulos I, et al |
| 32825119 | 2020 | Identification of Novel Fusion Genes in Bone and Soft Tissue Sarcoma and Their Implication in the Generation of a Mouse Model. | Teramura Y, et al |
