t(16;20)(p11;q13) FUS::NFATC2

Genes involved

FUS (16p11.2)

NFATC2 (20q13.2)

Tumor type

Ewing sarcoma

Ewing or Ewing-like sarcoma

simple bone cyst

Highly cited references

Pubmed IDYearTitleCitations
381894362024Vascular Neoplasms With NFATC1/C2 Gene Alterations : Expanding the Clinicopathologic and Molecular Characteristics of a Distinct Entity.54
310490202019EWSR1-NFATC2 and FUS-NFATC2 Gene Fusion-Associated Mesenchymal Tumors: Clinicopathologic Correlation and Literature Review.46
319725962020NKX3-1 Is a Useful Immunohistochemical Marker of EWSR1-NFATC2 Sarcoma and Mesenchymal Chondrosarcoma.39
310785632019EWSR1/FUS-NFATc2 rearranged round cell sarcoma: clinicopathological series of 4 cases and literature review.38
340810362021Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors: A Common Genomic Abnormality in Vascular Malformation/Hemangioma and Simple Bone Cyst.37
323620122020The clinical heterogeneity of round cell sarcomas with EWSR1/FUS gene fusions: Impact of gene fusion type on clinical features and outcome.32
388992832024Clinicopathological analysis of EWSR1/FUS::NFATC2 rearranged sarcoma in the left forearm: A case report.26
365558362022Implementation of Copy Number Variations-Based Diagnostics in Morphologically Challenging EWSR1/FUS::NFATC2 Neoplasms of the Bone and Soft Tissue.14
294311832018Transcriptomic definition of molecular subgroups of small round cell sarcomas.0
329913392020FUS-NFATC2 or EWSR1-NFATC2 Fusions Are Present in a Large Proportion of Simple Bone Cysts.0
382786062024Sarcomas with EWSR1::Non-ETS Fusion (EWSR1::NFATC2 and EWSR1::PATZ1).0
395762782025Emerging round cell sarcomas in children.0
333160982021Identification of EWSR1-NFATC2 fusion in simple bone cysts.0
378136492024A novel FUS::NFATC4 fusion detected in a sarcoma with morphological features overlapping with NFATC2 sarcomas.0
323277002020NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker.0
340893792021The role of molecular diagnostics in aneurysmal and simple bone cysts - a prospective analysis of 19 lesions.0
384330512024[Clinical, imaging and pathological and molecular characteristics of simple bone cyst].0
343440772021[Clinicopathological and molecular features of small round cell sarcoma of bone and soft tissue: a study of 72 cases].0

Bibliography

Pubmed IDPublication YearTitleAuthors
250102052014The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.Brohl AS, et al
294311832018Transcriptomic definition of molecular subgroups of small round cell sarcomas.Watson S, et al
329913392020FUS-NFATC2 or EWSR1-NFATC2 Fusions Are Present in a Large Proportion of Simple Bone Cysts.Pižem J, et al