t(1;7)(q32;q34) SLC45A3::BRAF

Genes involved

SLC45A3 (1q32.1)

BRAF (7q34)

Oncogenic mechanisms

Activation of MAPK pathway

Targeted therapy

Cobimetinib

trametinib

Tumor type

Prostate adenocarcinoma

Highly cited references

Pubmed IDYearTitleCitations
205263492010Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma.32

Bibliography

Pubmed IDPublication YearTitleAuthors
205263492010Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma.Palanisamy N, et al