t(10;22)(p11;q12) EWSR1::CREM
Tumor type
Angiomatoid fibrous histiocytoma
clear cell carcino
mamelanoma
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 23637631 | 2013 | Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. | 98 |
| 32997853 | 2021 | The spectrum of rare central nervous system (CNS) tumors with EWSR1-non-ETS fusions: experience from three pediatric institutions with review of the literature. | 91 |
| 40017677 | 2025 | A Case of Intracranial Mesenchymal Tumor, FET::CREB Fusion-positive, Diagnosed by Genomic Profiling with FoundationOne CDx. | 50 |
| 38291529 | 2024 | Potential prognostic determinants for FET::CREB fusion-positive intracranial mesenchymal tumor. | 45 |
| 28009602 | 2017 | EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location. | 42 |
| 33141488 | 2021 | Intracranial mesenchymal tumor with FET-CREB fusion-A unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocytoma-like neoplasms. | 39 |
| 36083250 | 2023 | Metastatic sporadic paraganglioma with EWSR1::CREM gene fusion: A unique molecular profile that expands the phenotypic diversity of the molecular landscape of the EWSR1::CREM gene fusion positive tumors. | 37 |
| 33616852 | 2021 | Clear Cell Odontogenic Carcinoma: First Report of Novel EWSR1-CREM Fusion Gene in Case of Long-Term Misdiagnosis. | 35 |
| 36966162 | 2023 | The oncogenic properties of the EWSR1::CREM fusion gene are associated with polyamine metabolism. | 32 |
| 35693189 | 2022 | Clinicopathological and Genomic Features of Pediatric Intracranial Myxoid Mesenchymal Tumor with both of EWSR1-CREM Gene Fusion and MAP3K13 Mutation: A Case Report and Comparison with Adult Cases in the Literature. | 29 |
| 39249507 | 2024 | Extra-abdominal and intra-abdominal FET::CREM fusion mesenchymal neoplasms: comparative clinicopathological study of 9 new cases further supporting a distinct potentially aggressive sarcoma and report of novel sites. | 29 |
| 28281318 | 2018 | Intracranial myxoid mesenchymal tumors with EWSR1-CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? | 29 |
| 29912715 | 2018 | Ectomesenchymal Chondromyxoid Tumor: A Neoplasm Characterized by Recurrent RREB1-MKL2 Fusions. | 28 |
| 38883514 | 2024 | Diagnostic Utility of EWSR1 in Clear Cell Odontogenic Carcinoma: A Systematic Review. | 28 |
| 34821426 | 2022 | Intracranial mesenchymal tumors with FET-CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas. | 27 |
| 32770123 | 2020 | EWSR1/FUS-CREB fusions define a distinctive malignant epithelioid neoplasm with predilection for mesothelial-lined cavities. | 24 |
| 34261344 | 2021 | Expression of Transcription Factor CREM in Human Tissues. | 22 |
| 35571637 | 2022 | A EWSR1-CREM-rearranged gastric mesenchymal tumor accompanied by gastritis cystica profunda and with probable benign behavior: a case report. | 20 |
| 34721908 | 2021 | A Case of Buccal Clear Cell Carcinoma Caused by Rare Fusion Gene: EWSR1-CREM. | 20 |
| 30219084 | 2018 | Detection of specific gene rearrangements by fluorescence in situ hybridization in 16 cases of clear cell sarcoma of soft tissue and 6 cases of clear cell sarcoma-like gastrointestinal tumor. | 18 |
| 34251595 | 2022 | Clear Cell Carcinoma in the Oral Cavity with Three Novel Types of EWSR1-ATF1 Translocation: A Case Report. | 18 |
| 37829338 | 2023 | Case report: The activity of multi-kinase VEGF inhibitor, Pazopanib, in metastatic undifferentiated round cell sarcomas harboring EWSR1::CREM fusion: clinicopathological series of two cases and literature review. | 17 |
| 38674190 | 2024 | Elucidating the Diagnostic Complexity of Round Cell Sarcoma with EWSR1-CREM Fusion: A Comprehensive Case Study. | 17 |
| 37097347 | 2023 | CREB fusion-associated epithelioid mesenchymal neoplasms of the female adnexa: three cases documenting a novel location of an emerging entity and further highlighting an ambiguous misleading immunophenotype. | 15 |
| 37274229 | 2023 | Primary pulmonary hyalinizing clear cell carcinoma with fusions of both EWSR1::CREM and IRF2::NTRK3: report of a case with an aggressive behavior. | 14 |
| 32970137 | 2020 | Intracranial Myxoid Mesenchymal Tumor/Myxoid Subtype Angiomatous Fibrous Histiocytoma: Diagnostic and Prognostic Challenges. | 14 |
| 34228212 | 2022 | Intra-abdominal EWSR1/FUS-CREM-rearranged malignant epithelioid neoplasms: two cases of an emerging aggressive entity with emphasis on misleading immunophenotype. | 13 |
| 39420989 | 2024 | Dermal cutaneous clear cell sarcoma defined by novel EWSR1-CREM fusion. | 11 |
| 33405400 | 2021 | Molecular Pathology of Salivary Gland Neoplasms: Diagnostic, Prognostic, and Predictive Perspective. | 0 |
| 32668333 | 2020 | Primary Intracranial Mesenchymal Tumor with EWSR1-CREM Gene Fusion: A Case Report and Literature Review. | 0 |
| 31305268 | 2019 | Expanding the Phenotypic Spectrum of Mesenchymal Tumors Harboring the EWSR1-CREM Fusion. | 0 |
| 36640048 | 2023 | Compound clear cell sarcoma with EWSR1::CREM fusion. | 0 |
| 37211641 | 2023 | Hyalinizing clear cell carcinoma of the lung with EWSR1::CREM fusion. | 0 |
| 33002291 | 2020 | EWSR1-CREM fusion in pulmonary mesenchymal neoplasm showing distinctive clear cell morphology. | 0 |
| 37151162 | 2023 | Ovarian epithelioid malignant peripheral nerve sheath tumor with EWSR1-CREM fusion: A case report and literature review. | 0 |
| 35165059 | 2022 | Detection of EWSR1 fusions in CCOC by targeted RNA-seq. | 0 |
| 31430747 | 2019 | Intracranial Myxoid Mesenchymal Tumor with Rare EWSR1-CREM Translocation. | 0 |
| 39868958 | 2025 | Myxoid spindle cell tumor with EWSR1-CREM fusion mimicking papillary adenoma of the lung. | 0 |
| 39888444 | 2025 | EWSR1::CREM rearranged intra-abdominal malignant epithelioid neoplasm: two new cases of an emerging entity with clinicopathological characteristics and histological pitfalls. | 0 |
| 37844955 | 2023 | One step at a time: Melanocytic differentiation in fusion-driven cutaneous neoplasms. | 0 |
| 34049318 | 2022 | Cytokeratin-positive Malignant Tumor in the Abdomen With EWSR1/FUS-CREB Fusion: A Clinicopathologic Study of 8 Cases. | 0 |
| 37818644 | 2024 | Expanding the Spectrum of EWSR1::CREM Fusion Tumors: An Unusual Pediatric Intranasal Myxoid Tumor. | 0 |
| 36318291 | 2023 | Retroperitoneal malignant extra-gastrointestinal neuroectodermal tumor with EWSR1::CREM fusion and IL-6-related systemic inflammatory symptoms: a case report. | 0 |
| 34258808 | 2021 | A case of intracranial myxoid mesenchymal tumor with EWSR1:CREM fusion in an adult female: Extensive immunohistochemical evaluation. | 0 |
| 36107277 | 2023 | An extracranial CNS presentation of the emerging "intracranial" mesenchymal tumor, FET: CREB-fusion positive. | 0 |
| 36328767 | 2023 | Systemic inflammation caused by an intracranial mesenchymal tumor with a EWSR1::CREM fusion presenting associated with IL-6/STAT3 signaling. | 0 |
| 34254369 | 2021 | Intracranial myxoid angiomatoid fibrous histiocytoma with "classic" histology and EWSR1:CREM fusion providing insight for reconciliation with intracranial myxoid mesenchymal tumors. | 0 |
| 34929603 | 2022 | Myoepithelial and oral intracranial myxoid mesenchymal tumor-like neoplasms as diagnostic considerations of the ever-expanding extracranial myxocollagenous tumors harboring FET-CREB fusions. | 0 |
| 33085975 | 2020 | Broadening the Age of Incidence of Intracranial Angiomatoid Fibrous Histiocytoma With EWSR1-CREM Fusion: A Case Report. | 0 |
| 29975250 | 2018 | Molecular Profiling of Hyalinizing Clear Cell Carcinomas Revealed a Subset of Tumors Harboring a Novel EWSR1-CREM Fusion: Report of 3 Cases. | 0 |
| 39648206 | 2024 | Malignant epithelioid tumors with EWSR1::CREB fusion involving the kidney: a report of two cases. | 0 |
| 36504225 | 2023 | A novel SMARCA2-CREM fusion expending the molecular spectrum of salivary gland hyalinazing clear cell carcinoma beyond the FET genes. | 0 |
| 35730186 | 2022 | Brain parenchymal angiomatoid fibrous histiocytoma and spinal myxoid mesenchymal tumor with FET: CREB fusion, a spectrum of the same tumor type. | 0 |
| 34405605 | 2021 | [Clinicopathological features and molecular genetic changes of lung salivary gland-type clear cell carcinoma]. | 0 |
| 38460673 | 2024 | Intra-Abdominal Epithelioid Neoplasm With EWSR1::CREB Fusions Involving the Kidney: A Clinicopathologic and Molecular Characterization With an Emphasis on Differential Diagnosis. | 0 |
| 39762170 | 2025 | [Intracranial mesenchymal tumors with FET::CREB fusion: a clinicopathological analysis of six cases]. | 0 |
Bibliography
| Pubmed ID | Publication Year | Title | Authors |
|---|
23637631
| Pubmed ID | Publication Year | Title | Authors |
|---|---|---|---|
| 33002291 | 2020 | EWSR1-CREM fusion in pulmonary mesenchymal neoplasm showing distinctive clear cell morphology. | Komatsu M, et al |
| 28009602 | 2017 | EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location. | Kao YC, et al |
| 30831299 | 2019 | Intracranial Angiomatoid Fibrous Histiocytoma with EWSR1-CREB Family Fusions: A Report of 2 Pediatric Cases. | Konstantinidis A, et al |
| 29975250 | 2018 | Molecular Profiling of Hyalinizing Clear Cell Carcinomas Revealed a Subset of Tumors Harboring a Novel EWSR1-CREM Fusion: Report of 3 Cases. | Chapman E, et al |
