RPL22 (ribosomal protein L22)

2003-02-01  

Identity

HGNC
LOCATION
1p36.31
LOCUSID
ALIAS
EAP,HBP15,HBP15/L22,L22
FUSION GENES

Other Information

Locus ID:

NCBI: 6146
MIM: 180474
HGNC: 10315
Ensembl: ENSG00000116251

Variants:

dbSNP: 6146
ClinVar: 6146
TCGA: ENSG00000116251
COSMIC: RPL22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116251ENST00000234875P35268
ENSG00000116251ENST00000462296K7EP65
ENSG00000116251ENST00000465335K7EJT5
ENSG00000116251ENST00000465387K7ELC4
ENSG00000116251ENST00000471204K7EMH1
ENSG00000116251ENST00000497965K7ERI7

Expression (GTEx)

0
100
200
300
400
500
600

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

References

Pubmed IDYearTitleCitations
352302142022L22 ribosomal protein is involved in dynamin-related protein 1-mediated gastric carcinoma progression.1
352302142022L22 ribosomal protein is involved in dynamin-related protein 1-mediated gastric carcinoma progression.1
342208632021RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.3
342208632021RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.3
298605802020Intratumoral Heterogeneity of RPL22 Frameshift Mutation in Colorectal Cancers.0
323835352020Post-transcriptional regulation of C-C motif chemokine ligand 2 expression by ribosomal protein L22 during LPS-mediated inflammation.7
298605802020Intratumoral Heterogeneity of RPL22 Frameshift Mutation in Colorectal Cancers.0
323835352020Post-transcriptional regulation of C-C motif chemokine ligand 2 expression by ribosomal protein L22 during LPS-mediated inflammation.7
308744622019Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex.9
308744622019Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex.9
248409522014Interaction of ribosomal protein L22 with casein kinase 2α: a novel mechanism for understanding the biology of non-small cell lung cancer.6
251963642014High frequency of RPL22 mutations in microsatellite-unstable colorectal and endometrial tumors.31
248409522014Interaction of ribosomal protein L22 with casein kinase 2α: a novel mechanism for understanding the biology of non-small cell lung cancer.6
251963642014High frequency of RPL22 mutations in microsatellite-unstable colorectal and endometrial tumors.31
231279732013Frequent mutations in the RPL22 gene and its clinical and functional implications.43

Citation

Dessen P

RPL22 (ribosomal protein L22)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/136/js/lib/favicon/apple-touch-icon.png